Anti-Epileptic Drugs, Would They be the Cause of Heterotopic Ossification

Progression of Heterotopic Ossification around the Elbow after Trauma

 Background: This study addresses the null hypothesis that there is no expansion of heterotopic ossification (HO) in the elbow beyond what can be seen early on.   Methods: The area of HO was measured on lateral radiographs of 38 consecutive patients that had operative treatment of HO between 2000 and 2013. Measurements from radiographs obtained between 3 to 7 weeks were compared to measurements...

Newer anti-epileptic drugs.

NEED AND PURPOSE OF REVIEW A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA MEDLINE search (1966-2013) was performed using terms newer anti-epileptic drugs, Oxcarbazep...

Heterotopic Ossification

Heterotopic Ossification

Heterotopic ossification is a complicated and significant medical problem characterized by abnormal growth of bone in soft tissues. It occurs most commonly around a joint following surgery or trauma and is one of only a few benign conditions commonly treated with radiation therapy. In its severe form, the condition causes pain, loss of function, and restricted range of motion in the affected jo...

New anti-epileptic drugs.

Epilepsy represents the most common serious neurological disorder, with a prevalence of 0.4 - 1%. Approximately 30% of patients are resistant to currently available drugs. New anti-epileptic drugs are needed to treat refractory epilepsy, improve upon current therapies, improve the prognosis of epilepsy and to prevent the epileptogenic process. Designing compounds with specific physiological tar...